About Dr Hotton

Professional History

Dr Gary Hotton qualified from University College and Middlesex School of Medicine in 1995. His general medical training was undertaken at Dundee Royal Infirmary and the Royal Free Hospital. Following this he spent seven years in research at Kings College Hospital and Imperial College London. He then returned to specialist training in London and joined the specialist register in May 2010. He has been employed in an NHS Consultant post between The National Hospital of Neurology and Neurosurgery and The North Middlesex University Hospital NHS Trust since June 2010.

Qualifications

	1992	B.Sc. 2(i) (Hons) in Anatomy (Neuroscience)	University College London
	1995	MB BS	University College London
	1998	MRCP	Royal College of Physicians
	2008	M.D.	University of London
	2009	Specialty Certificate in Neurology	Royal College of Physicians
	2010	CCT Neurology	Royal College of Physicians

Awards

	1981	Baron De Lancy and De La Hanty Foundation Scholarship
	1991	Thorn Scholarship in recognition of pre-clinical study
	1991	Distinction in Neuroanatomy
	1993	Certificate of Merit for Medicine and Surgery
	2006	William Koller Award for innovative research (Movement Disorder Society)

Publications

Original Articles

• Gill S, Patel N, Hotton G, O'Sullivan K, McCarter R, Bunnage M, Brooks D, Svendson C, Heywood P. Direct Infusion of glial cell line derived neurotrophic factor (GDNF) in Parkinson's Disease. Nat Med. 2003:9:589-595.
  
  
• Williams D, Kuhn A, Kupsch A, Tijssen M, van Bruggen G, Speelman H, Hotton G, Yarrow K, Brown P. Behavioural cues are associated with modulations of synchronous oscillations in the human subthalamic nucleus. Brain. 2003;126:1975-1985.
  
  
• O'Gorman R, Selway R, Reid C, Hotton G, Hall E, Jarosz J, Polkey C, Hill D. Registered computed tomography images as an alternative to postimplantation magnetic resonance Imaging in the assessment of subthalamic electrode placement. J Comput Assist Tomogr.2004;28:548-550.<
  
  
• Williams D, Kuhn A, Kupsch A, Tijssen M, van Bruggen G, Speelman H, Hotton G, Loukas C, Brown P. The relationship between oscillatory activity and motor reaction time in the parkinsonian subthalamic nucleus. Eur. J. Neurosci. 2005;21:249-258.
  
  
• Love S, Plaha P, Patel NK, Hotton GR, Brooks DJ, Gill SS. Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain. Nat Med 2005;11(7):703-704.
  
  
• Silberstein P, Pogosyan A, Kuhn AA, Hotton G, Tisch S, Kupsch A, Dowsey-Limousin P, Hariz M, Brown P. Cortico-cortical coupling in Parkinson's disease and its modulation by therapy. Brain 2005;128(6):1277-1291.
  
  
• Gerhard A, Pavese A, Hotton G, Turkheimer F, Es M, Hammers A, Eggert K, Oertel W, Banati RB, Brooks DJ. In vivo imaging of microglial activation with [11C] (R) -PK11195 PET in idiopathic Parkinson's disease. Neurobiology of Disease 2006; 21(2): 404-12.
  
  
• Lang AE, Gill S, Patel NK, Lozano A, Nutt JG, Penn R, Brooks DJ, Hotton G, Moro E, Heywood P, Brodsky MA, Burchiel K, Kelly P, Dalvi A , Scott B , M Stacy M, D Turner D, Wooten V GF, Elias WJ, Laws ER, Dhawan V , Stoessl AJ, Matcham J; Coffey RJ; Traub M. A multicenter, randomized, double-blind, placebo-controlled trial of Liatermin (r metHuGDNF) administered by bilateral intraputaminal infusion to patients with idiopathic Parkinson's disease. Annals of Neurology 2006; 59(3): 459-466.
  
  
• Edison P, Archer H, Hinz R, Hammers A, Pavese N, Tai Y, Hotton G, Fox N, Kennedy A, Rossor M, Brooks DJ. Amyloid deposition and metabolic dysfunction in Alzheimer's disease and mild cognitive impairment: An 11C-PIB and 18F-FDG PET study. Neurology 2007; 68(7): 501-8.
  
  
• Pavese N, Evans A, Tai YF, Hotton GR, Brooks DJ, Lees AJ, Piccini P. Clinical correlates of levo dopa-induced dopamine release in Parkinsons disease. A 11C-raclopride PET study. Neurology 2006; 67(9): 1612-7.
  
  
• Thobois S, Hotton G, Pinto S, Wilkinson L, Limousin-Dowsey P, Brooks DJ, Jahanshahi M. In Parkinson's disease, subthalamic nucleus stimulation alters pallidal coupling with prefrontal, cingulate, and temporal cortices during random number generation. JCBFM 2007; 27(6): 1173-84.
  
  
• Mínguez-Castellanos A, Escamilla-Sevilla F, Hotton GR, Toledo-Aral JJ, Ortega-Moreno A, Méndez-Ferrer S, Martín-Linares JM, Katati MJ. Carotid body autotransplantation in Parkinson's disease: A clinical and PET study. JNNP. 2007; 78(8): 825-31.
  
  
• Hammers A, Asselin MC, Turkheimer FE, Hinz R, Osman S, Hotton G, Brooks DJ, Duncan JS, Koepp MJ. Balancing bias, reliability, noise properties and the need for parametric maps in quantitative ligand PET: [(11)C] diprenorphine test-retest data. Neuroimage. 2007; 38(1):82-94.
  
  
• Sawamoto N, Piccini P, Hotton G, Pavese N Thielmans K, Brooks DJ. Cognitive deficits and striato-frontal dopamine release in Parkinson's disease. Brain. 2008;131(5):1294-1302.
  
  
• Pavese N, Moore RY, Scherfler C, Khan NL, Hotton G, Quinn NP, Bhatia KP, Wood NW, Brooks DJ, Lees AJ, Piccini P. In vivo assessment of brain monoamine systems in parkin gene carriers: a PET study. Exp Neurol. 2010; 222(1):120-4.
  
  
• Ahmed I, Bose SK, Pavese N, Ramlackhansingh A, Turkheimer F, Hotton G, Hammers A, Brooks DJ. Glutamate NMDA receptor dysregulation in Parkinson's disease with dyskinesias. Brain. 2011;134(4):979-986.
  
  
• Patel N, Pavese N, Javed S, Hotton G, Brooks D, Gill S. Benefits of putaminal GDNF infusion in Parkinson disease are maintained after GDNF cessation. Neurology. 2013 81(13):1176-8. Devine M, Bentley P, Jones B, Hotton G, Greenwood R, Jenkins I, Joyce E, Malhotra P. The role of the right inferior frontal gyrus in the pathogenesis of post-stroke psychosis. J Neurol. 2014 Mar;261(3):600-3.
  
  

For abstracts visit www.ncbi.nlm.nih.gov/pubmed/?term=hotton+g

Reviews

• Hotton G. Anti-epileptic drug treatment for patients with brain-tumour-related epilepsy. Neuro-Oncology. Key Opinions in Medicine. 2013;1: 1-4.

Book Chapters

• Hotton G and Clough C. Other Drug Related Movement Disorders in Drug Related Movement Disorders ed. K. Sethi. Marcel Decker 2004.